Overview

The research interests of the Rose lab are centered on the structure, function and metabolism of plant cell walls and their pivotal roles in growth, development and interactions with pathogens. Additionally, cellulosic cell walls represent a central component of the biofuels industry, as well as providing the building blocks for a broad range of plant-derived products.

Research Focus

The Rose research group has been developing a suite of functional genomics and proteomics tools to advance cell wall research; identifying and characterizing novel cell wall proteins with diverse and currently unknown and unexploited functions. We are now developing a more comprehensive catalog and functional inventory of the plant cell wall proteome, or secretome, using fruit development and ripening, and potential bioenergy crops and two key experimental systems. Our lab is also heavily invested in sustainable biofuels research, developing analytic methods for profiling wall composition and bioethanol potential of diverse feedstocks. We are taking a lead role in coordinating biofuels research among Cornell plant scientists.

Instruction Focus

Dr. Rose co-teaches Plant Biochemistry (Dr. Rose teaches a graduate level module ( "The Plant Cell Wall: from Structure to the Proteome "; BioPL 482.7) and co-teaches both "Plant Biochemistry " (BioPL 462) and the introductory plant biology graduate module "Concepts and Techniques in Plant Molecular Biology " (Bio PL 653.1). Dr. Rose also teaches a summer workshop on the Cornell campus on plant proteomics and biofuels. In 2007 Dr. Rose was an invited instructor for the Cold Spring Harbor Plant Molecular Techniques summer course, providing 2 day class and laboratory instruction in biofuels and plant cell wall analysis.

Additional Links

• Rose Lab Website
• Secretom
• Link to CALS Research portal
• Link to CALS Impact statements

Honors, Awards and Appointments

• Plant Biology Graduate Students' Award for Excellence in Mentoring (2006) - 2006
• International Research Fellowship, Generalitat Valenciana, Spain - 2005
• Japanese Society for the Promotion of Science (JSPS) fellowship - 2001

Professional Activities

• Editorial board member of Plant Physiology -
• Editorial board member of Annual Plant Reviews -
• Invited member of Faculty of 1000 (www.facultyof1000.com/about/members/8029) -
• Executive committee for NE Sun Grant Institute of Excellence (www.nesungrant.cornell.edu) -
• Invited instructor for the Cold Spring Harbor Laboratory "Molecular Techniques in Plant Science " training course, focusing on plant cell wall analysis 2007 (http://meetings.cshl.edu/courses/c-plan07.shtml) -

Selected Publications

• Urbanowicz, B.R., Catala, C., Irwin, D., Wilson, D.B., Ripoll, D.R. and Rose, J.K.C. (2007) A tomato endo-B-1,4-glucanase, SlCel9C1, represents a distinct subclass with a new family of carbohydrate binding modules (CBM49). Journal of Biological Chemistry 282: 12066-12074.
• Urbanowicz, B.R., Bennett, A.B., Catala, C., del Campillo, E., Hayashi, T., Henrissat, B., Hofte, H., McQueen-Mason, S., Patterson, S., Shoseyov, O., Teeri, T. and Rose, J.K.C. (2007) Structural organization and a standardized nomenclature for plant endo-1,4-B-glucanases of glycosyl hydrolase family 9. Plant Physiology (in press).
• Saladie, M., Rose, J.K.C., Cosgrove, D.J. and Catal?, C. (2006) Characterization of a new xyloglucan endotransglucosylase/hydrolase (XTH) from ripening tomato fruit and implications for the diverse modes of enzymic action. The Plant Journal 47: 282-295
• Isaacson, T., Saravanan, R.S., He, Y., Damasceno, C.M.B., Catala, C., Saladie, M. and Rose, J.K.C. (2006) Sample extraction techniques for enhanced proteomic analysis of plant tissues. Nature Protocols 1: 769-774.
• Tyler, B.M. et al. (2006) Phytophthora genome sequences uncover evolutionary origins and mechanisms of pathogenesis. Science 313: 1261-1266.
• Lee, S.-J. Kelley, B., Damasceno, C.M.B., St. John, B., Kim, B.-S. Kim, B.-D. and Rose, J.K.C. (2006) A functional screen to characterize the secretomes of eukaryotic phytopathogens and their hosts in planta. Molecular Plant Microbe Interactions 12: 1368-1377.
• Stenvik, G.-E., Butenko, M.A., Urbanowicz, B.R., Rose, J.K.C. and Aalen, R.B. (2006) Overexpression of INFLORESCENCE DEFICIENT IN ABSCISSION activates cell separation in vestigial abscission zones in Arabidopsis. The Plant Cell 18: 1467-1476.
• Lee, S.J., Kim, B.-D. and Rose, J.K.C. (2006) Identification of eukaryotic secreted and cell surface proteins using the yeast secretion trap screen. Nature Protocols 1: 2439-2447.
• Saladie, M., Matas, A.J., Isaacson, T. Jenks, M.A., Goodwin, S.M., Niklas, K.J., Xiaolin, R., Labavitch, J.M., Shackel, K.A., Fernie, A.R., Lytovchenko, A., O`Neill, M.A., Watkins, C.B. and Rose, J.K.C. (2007) A re-evaluation of the key factors that contribute to tomato fruit softening and integrity. Plant Physiology 144: 1012-1028.
• Isaacson, T. and Rose, J.K.C. (2006) The plant cell wall proteome, or secretome. In Plant Proteomics. Annual Plant Reviews Series. Ed. Finnie, C., Pub. Blackwell Publishing 28:185-209.

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